Job Description General Summary: The Manager role will work cross-functionally to develop and maintain visual content to effectively communicate data for publication for medical congresses and journals and other external audiences (e.g., regulatory authorities). Key Duties and Responsibilities: Interpret routine technical, scientific, and medical concepts into visual content. Provide design knowledge to develop various types of routine digital and print content (e.g., tables, figures, poster layout) with minimal supervision for internal and external audiences using new or pre-defined layouts. Critically reviews files for finalization (e.g., versioning, retouching, updating design assets, resizing, quality control review, proofing, and pre- and post-production) to ensure compliance and consistency. Proactively anticipates risks, solves routine problems, and contributes to process improvements. Manage multiple design projects simultaneously while adhering to project timelines. Maintain a comprehensive repository of design assets and files for consistency across file naming, taxonomy, organization, tracking, and version control. Maintain digital and print templates, including branding guidelines. Ensure quality and timely delivery from print vendors. Knowledge and Skills: Ability to simplify ideas, information, and data into concise clear visuals. Ability to simplify moderately complex ideas, information, and data into concise clear visuals. Strong knowledge of and experience with various technologies, including Adobe Creative Suite (InDesign, Photoshop, Illustrator, Premiere), Acrobat Pro DC, Microsoft Office Suite (PowerPoint, Word, Excel), SharePoint, Veeva, and iEnvision (Datavision). · Understanding of typography, color theory, and layout principles. Familiarity and experience with production, print processes, and dissemination techniques. Fluency in PC and Mac environments. · Excellent attention to detail, and strong copyediting skills and ability to apply design principles to digital or print layouts. Strong verbal communication skills and the ability to collaborate effectively with cross-functional teams. Strong organizational skills including the ability to prioritize competing activities in a fast-paced, deadline-driven environment with multiple priorities. Excellent organizational skills including the ability to prioritize competing activities in a fast-paced, deadline-driven environment with multiple priorities. Ability to troubleshoot problems with minimal supervision. Ability to adapt and grow in a fast paced and dynamic work environment. A portfolio demonstrating strong graphic design, brand, and ideally, scientific examples that show knowledge of design techniques and communications principles. Education and Experience: Bachelor’s degree required, in graphic arts, design, communications, or related field Typically requires 4 years of work experience, or the equivalent combination of education and experience. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $124,100 - $186,100 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected] Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 17 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

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