Job Description General Summary: Vertex is seeking a Principal Analyst, G&A Technology to support our Legal, OBIE, and Corporate Communications functions. In this role, you will partner closely with stakeholders to deliver technology solutions that strengthen operations, enhance the user experience, and support strategic priorities across corporate functions, with a particular focus on Legal, Compliance and Corporate Communication needs. The ideal candidate combines deep expertise in technology delivery, stakeholder engagement, and cross-functional leadership with a proven track record of partnering with Legal, Compliance, and Corporate Communications organizations in complex, highly regulated environments. This person will translate business needs into scalable technology solutions, lead initiatives from planning through execution, and help ensure solutions align with regulatory, privacy, data integrity, and governance requirements. Familiarity with Gen AI tools and prompt engineering is a plus to support evolving business needs and productivity opportunities. Key Duties and Responsibilities: Lead end-to-end delivery of technology initiatives, from requirements gathering through implementation and post-go-live support. Partner with business stakeholders to understand priorities, challenges, and opportunities. Manage relationships with strategic software vendors, implementation partners, and managed service providers. Serve as a trusted advisor by translating business needs into technology solutions and delivery plans. Drive project planning, execution, risk management, issue resolution, and stakeholder communication across multiple initiatives. Provide functional and technical expertise in application configuration, integrations, and documentation. Partner with Privacy, Compliance, and Internal Audit to ensure adherence to applicable regulations, data integrity standards, and system lifecycle and change management processes. Contribute to roadmap planning, prioritization, and continuous improvement across G&A Technology. Required Qualifications Bachelor’s degree in a technology-related field or equivalent experience. 8+ years of experience supporting business systems, preferably in life sciences or another regulated industry. Experience supporting Legal, Compliance, and Corporate Communication functions. Proven ability to deliver complex technology initiatives with cross-functional and global stakeholders. Experience translating business needs into scalable technology solutions. Experience with SaaS platforms, enterprise applications, integrations, and vendor-supported solutions, including iManage, Everlaw, Jasper AI, PwC Interactions Hub, and PoliteMail. Strong stakeholder management, communication, and problem-solving skills. Experience working in regulated environments with attention to compliance, privacy, data integrity, and governance. Ability to work effectively in a matrixed environment and drive results. Preferred Qualifications Experience in biotechnology, pharmaceuticals, or other highly regulated industries. Experience supporting Legal, Compliance, or Corporate Communication functions in a corporate environment. Demonstrated experience evaluating, implementing, and supporting AI-powered solutions, including Generative AI (GenAI), intelligent assistants, copilots, chatbots, SaaS-based AI solutions, and agentic AI technologies. Knowledge of enterprise architecture principles and systems integration concepts. Experience with Agile, hybrid, or waterfall delivery methodologies. Understanding of data privacy, records management, and information governance. Ability to influence across teams and organizational boundaries without direct authority. Technical Skills Required Enterprise application implementation and support Application configuration and systems integration SaaS platforms and vendor-supported solutions Project delivery and execution Risk, issue, and dependency management Change management and user enablement Familiarity with Gen AI tools and prompt engineering #LI-HYBRID At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $142,800 - $214,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

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