Job Description General Summary: The Associate Director will be responsible for delivering commercial insights to inform strategic choices and commercial decisions in hemoglobinopathies (SCD/TDT) and other categories. As an integral member of the commercial strategy team and extended brand team, the Associate Director will maintain a pulse on critical business questions to formulate and execute an insights plan (involving either primary market research or data analytics) to answer them. This is a hybrid/on-site role based in Boston, MA (3 days onsite, 2 days remote on a weekly basis). Key Duties and Responsibilities: Function as a key partner and provide objective perspective and insights to cross-functional teams (marketing, global commercial strategy, commercial business unit) Formulate a comprehensive insights generation plan to address a spectrum of business questions using the appropriate methodology Independently design and execute primary market research that addresses key business questions Define data analytics needed to answer ongoing business questions and oversee its execution Support the analytics coordination forum which provides cross-functional alignment on analytics activities supporting the program Maintain a current summary of all the insights supporting a disease area in the form of an Insights book Develop the situation analysis for the Brand Planning process Maintain a strong understanding of the LRP forecast model and provide assumptions that inform the Long-Range Plan Knowledge and Skills: Depth of knowledge in a variety of primary market research methodologies; substantial experience managing design and execution of primary market research projects Strong complex quantitative analysis skills; experience running own analyses as well as partnering with advanced analytics professionals, and interpreting results Domain knowledge of real-world data (large scale open or closed insurance claims, EHR), and/or other related data sources from providers and health systems Experience working in rare disease and knowledge of cell & gene therapies Past US launch and inline brand experience strongly preferred Exceptional written and verbal communication skills – able to synthesize and distill complex information into a compelling narrative Proactive orientation - able to anticipate issues, engage with stakeholders and plan accordingly Demonstrated experience as a trusted advisor and thought partner to stakeholders Comfortable with ambiguity; able to effectively structure problems and solution approaches Education and Experience: Bachelor’s Degree in relevant discipline required Typically requires 8 or more years in bio-pharma marketing, market research and/or analytics, management consulting, or the equivalent combination of education and experience At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $157,800 - $236,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

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