Compensation: Chicago/National: $100,000-$135,000 SF/NY: $115,00-$150,000 Tempus AI is a cutting-edge clinical laboratory coupled with powerful automation capabilities. We continually strive to deliver quality results to our patients as quickly as possible. As a Senior QA Engineer, you will embed with one or more Agile Scrum teams to validate and continuously improve our in-house developed software. This is a hands-on engineering role: you will design and maintain UI, API, and data-validation test frameworks in Java and Python, wire them into CI/CD so they run unattended against every build. You will gain experience with modern test tooling, cloud-native delivery, and AI-assisted testing. Knowledge of genetic testing, molecular biology, or other scientific disciplines is a strong plus but is not required. This is a fantastic opportunity to engage in a positive and creative work environment that offers great benefits and opportunities for growth. Key Responsibilities Participate with your teams in Agile Scrum ceremonies, including backlog grooming, sprint planning, and retrospectives; represent quality and testability from the start of a story, not at the end of the sprint. Build and maintain automated tests for web UI, REST APIs and databases, and hold test code to the same standards as production code. Own the regression suites for your applications: grow coverage, fix or remove flaky tests, and keep them running in CI/CD after every deployment and nightly. Test for HIPAA and SOX compliance, including how PHI is handled, who can access it and what gets logged, and keep tests traceable to requirements. Analyze test results and triage failures quickly: separate real product defects from environment, data, and test-harness issues, identify root cause, and drive resolution with clear, reproducible bug reports. Validate scheduled night-time and off-hours deployments, and confirm post-deployment health in lower and production environments. Participate in risk assessments, validation processes, and release readiness reviews; provide a clear, evidence-based go/no-go quality recommendation. Maintain traceability from requirements and specifications through test cases to results, especially for regulated components. Apply AI-assisted tooling responsibly to accelerate test authoring, failure triage, and coverage analysis, while remaining accountable for the correctness of every test that ships. Mentor junior QA engineers through pairing and code review, and help internal users troubleshoot when needed. Qualifications 8+ years in software QA, including 5+ years writing test automation. Strong programming ability in at least one language used for automation, Java and/or Python preferred Hands-on UI automation with Playwright or Selenium. API testing with REST Assured, Postman or similar, including schema, contract and authentication checks. Experience running tests in CI/CD (GitHub Actions, Jenkins, GitLab CI or similar), with reporting such as Allure. Solid SQL (e.g., MySQL) and a careful approach to test data when it's regulated. Experience with performance and load testing using tools such as JMeter, k6, or Gatling. Working knowledge of HIPAA, HL7 and FHIR. Bachelor's degree in Computer Science or a related field, or equivalent experience. Preferred ISTQB/ASTQB certification. Experience with AWS (ECS/Fargate, Lambda, S3) or Azure, and with Docker. Experience in a regulated environment such as a CLIA/CAP lab, FDA, SOX. PRIVACY NOTICES To review Ambry’s Privacy Notice, Click here: https://www.ambrygen.com/legal/privacy-policy To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics To review the UKG privacy notice, click here: California Privacy Notice | UKG Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster. At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program. The Company reserves the right to make changes to the 401k plan from time to time. You can learn more about the benefits here. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment. The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. For the purpose of the above job description, “Essential Functions” are “Material Job Duties”. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at careers@ambrygen.com Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly. To review Ambry’s Privacy Notice, click here: Ambry’s Privacy Notice To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics

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19 Oct, 2026

ambrygen.com

Senior Software Engineer (Platform Engineering)-Remote, USA

Senior level
Remote
DevOps & Infra

$130k–150k/yr

Remote - California, United States of America

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