Cellular Biologist II The Jackson Laboratory | NYSCF New York, New York   We're hiring a Cellular Biologist II to join our Oncology lab, where you'll work hands-on with patient-derived organoids to support cutting-edge research on new and more effective cancer treatments. The Cellular Biologist II works directly under the supervision of the Senior Research Scientist and alongside a team of experienced cellular biologists and cellular specialists. In this production-focused role, you will interact with an interdisciplinary team of stem cell biologists, data scientists, automation engineers, and software developers in one of the most advanced automated platforms for cell biology worldwide. The range of duties includes, but is not limited to, project planning, developing methodologies, conducting automated procedures, modifying and updating procedures as needed, data collection and analysis, creating and revising documentation, contributing to reports and manuscripts for publications, and providing communication and instruction. You demonstrate and model effective mental concentration and visual attention. The Cellular Biologist II is expected to lead and mentor junior technical staff and departmental assistants. The Cellular Biologist II may be required to work flexible shifts that may include evenings, weekends, and/or holidays depending on the demands of the research project and/or laboratory operations. Responsibilities: Primary responsibilities are to perform automated and manual cell culture and related activities. Sets direction for workflows; serves as technical authority; resolves complex deviations; drives optimization and innovation. Exercises expert judgment in designing experimental or production modifications and is responsible for high-level troubleshooting. Examples of cell culture activities include the handling and processing of primary materials, such as tumor tissues and blood samples, as well as the culturing of tissue-derived organoids, fibroblasts and induced pluripotent stem cells (iPSCs). Work collaboratively to perform all necessary protocols for organoid derivation, fibroblast expansion, iPSC expansion and QC, and differentiations on the robotic platform(s) or manually as required. Additional project-related activities include, contributing to molecular, phenotypic, imaging assays, and other in vitro assays such as automated drug screenings using 3D organoid systems. Contribute to the design and optimize organoid co-culture protocols to model the tumor and tissue microenvironments Related activities include the storage and withdrawal of specimens from liquid nitrogen and freezers, and the preparation of media and reagents required for daily work. You will work closely with the laboratory operations team to ensure reagents/consumables inventory is accurately and efficiently supplied. Plan and monitor resources needed to operate; maintain inventory control; coordinate space and field questions. You may be required to participate in the monitoring and tracking of resources/expenditures across projects. Documentation of results; identify problems, troubleshoot, and analyze variations observed and reported in regular testing protocols. Leads modification, refinement, and adaptation of techniques and procedures, partnering with engineers and other staff to define and implement large-scale improvements. Documentation and feedback is provided in a variety of ways including the creation and modification of SOPs, filing of tickets to software and automation teams, and leading inter- and intra-team meetings. Lead the exchange of information through demonstration and instruction. Other duties as assigned. Qualifications: Experience with human/mammalian cell culture, 3D culture systems, and iPSC culture with additional broad expertise in cell and molecular biology techniques, is required. While not required, experience with liquid handling automation is preferred. Demonstrated ability to develop and improve biological workflows/processes, or have contributed to the development of automation/software tools. Demonstrated ability in coordinating and performing multiple, concurrent assignments across highly complex workflows in multi-faceted projects. Ability to work in a fast-paced environment and interact with all individuals in a productive, professional, and positive manner to enhance the outcome of the goals of the research program. Experience Required: 2 years Experience Preferred: 3 years Education Required: Bachelor’s Degree Education Preferred: Master’s Degree Pay Range: $49163 - $82311 per year, depending upon experience  -Please submit a Cover Letter and CV/ Resume with your application for consideration- About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California, New York, Florida), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org. EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws. Bar Harbor: The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries. Ellsworth: The Charles E. Hewett Center in Ellsworth, Maine, is a state-of-the-art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice. Ellsworth, Maine, is one of Maine’s fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year-round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants. Farmington: JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup. JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports. Sacramento: The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums. Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year. Augusta: JAX’s Maine Cancer Genomics Initiative (MCGI) is located in Augusta, Maine, in the Harold Alfond Center for Cancer Care (HACCC), at Maine General Hospital. It began operations in 2016 with three overarching goals: to provide cancer genomic testing for Maine cancer patients; to develop and deliver physician education about clinical genomic cancer diagnostics; and to build a network in Maine of oncology practices conducting studies in genomic medicine.

Cellular Biologist II.

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