Why Sarepta? Why Now? Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne Muscular Dystrophy and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our next-generation siRNA platform is focused on chronically administered therapies for neurodegenerative and pulmonary diseases. We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role We are seeking an experienced procurement leader to join Global Procurement and Strategic Sourcing as Associate Director, CMC Procurement. Reporting to the Director, Procurement CMC Outsourcing, this newly created role will align siRNA procurement strategy and translate complex supplier and spend decisions into disciplined execution with measurable business impact. The Associate Director, Procurement CMC Outsourcing develops and executes strategic sourcing strategies for CDMOs and CMOs supporting Manufacturing and Process Development. The role leads supplier identification, selection, negotiation, contracting, relationship management, and spend consolidation in partnership with cross-functional stakeholders. Working closely with business partners, the Associate Director translates priorities and needs into initiatives that support advancing Sarepta’s siRNA pipeline and responsible resource stewardship. The Opportunity to Make a Difference Primary Responsibilities Include: Business Partnering · Builds productive, collaborative relationships with Clinical and Commercial Manufacturing and Process Development business partners and stakeholders to align prioritization and lead execution of procurement initiatives · Develops relationships with external key suppliers/CDMOs/CMOs to identify opportunities to gain efficiency, drive cost savings, proactively respond to business needs, and reduce risk while fulfilling business requirements Category Management · Supports the development of category and sourcing strategies for siRNA program advancement, clinical material supply, and commercial launch readiness. · Identifies potential C(D)MOs for new programs and secures appropriately sized capacity for products at each stage of development · Leads category strategy implementation as well as value creation initiatives in support of business priorities · Delivers cost savings across the end-to-end supply chain and product lifecycle · Supports cross-functional teams with identification of supplier risks covering quality and compliance, technology-transfer readiness, process portability, capacity and scheduling, business continuity, geographic exposure, financial stability, and operational constraints; develops and tracks mitigation and contingency plans where necessary · Ensures accurate reporting of Procurement key performance measures (operational metrics, savings, quality, customer service, etc.) for the category and tracks ROI · identifies COGS savings opportunities and drives implementation RFx and Contract Negotiation · Leads end-to-end RFI and RFx activities, including market landscaping, supplier prequalification, scope development, bid management, cross-functional evaluation criteria, score calibration, due diligence, scenario analysis, and documented supplier recommendations · Leads negotiations of clinical and commercial supply agreements with key suppliers/CMOs/Labs, and drives prioritization alignment across Business, Finance and Legal and external partners. · Prepares and implements advanced negotiation strategies. Manages complex negotiations on price and terms, partners with stakeholders and Legal to negotiate and finalize agreements. SRM · Manages the Supplier/CMO Performance/Relationship Management process and ensures performance and accountability are tracked and improved. · Maximizes the value of strategy supplier relationships through structured governance, performance reviews, and continuous-improvement initiatives · Develops and maintains strong vendor relationships to ensure continuity of supply and innovation in processes. More about You Desired Education and Skills: Education and Experience BA/BS degree in a related field. MS or MBA preferred. 10+ years of relevant sourcing or procurement experience in the pharmaceutical or biotech industry. Skills and Competencies Experience independently leading the RfP process from market landscape through selection and contracting Demonstrated understanding of GMP requirements and international supply chain complexity Experience working with stakeholders/partners at all levels across the organization. In-depth strategic and operational procurement experience with knowledge of category management Outstanding communication skills with the ability to build coalition and influence with technical functions Experience with drug substance and drug product production of oligonucleotides, antibody oligonucleotide conjugation, and/or siRNA manufacturing preferred Experience independently negotiating various contracts, including, but not limited to, Master Services Agreements, Supply Agreements, and Statements of Work. Strong business acumen and financial analysis capabilities; ability to develop solid business cases to demonstrate the value proposition to move forward with project investment. Advanced skills with Microsoft Office Applications; Word, Excel, Powerpoint, and Outlook. Experience with Copilot or other AI tools preferred What Now? We’re always looking for solution-oriented, critical thinkers. So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Hybrid This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time. The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify. Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our deep pipeline is driven by our multi-platform technologies in siRNA, RNA and gene therapy. For more information, please visit www.sarepta.com or follow us on Twitter, LinkedIn, Instagram and Facebook.

Associate Director, CMC Procurement.

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