COMPANY: At BioCryst, we share a deep commitment to improving the lives of people living with hereditary angioedema (HAE) and other rare diseases. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and injectable protein therapeutics. Our global headquarters is in Durham, North Carolina, we have a regional office in Boston, Massachusetts, and our employees span the globe across sites in multiple countries. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit our website at www.biocryst.com or follow us on LinkedIn and Instagram. JOB SUMMARY: The Sr. Paralegal, Generalist provides broad-based legal and operational support across the Legal and Compliance function. This role supports contract lifecycle activities, manages discrete legal and compliance-related projects, and serves as a key coordination point between attorneys, business stakeholders, and external partners. The position operates in a highly collaborative and fast-paced, regulated environment. ESSENTIAL DUTIES & RESPONSIBILITIES: Contracting & Legal Support · Support the end-to-end contract lifecycle, including intake, tracking, drafting support, review coordination, execution, and archival of agreements. · Prepare, review, and negotiate assigned high volume agreements (e.g., NDAs, employment agreements, separation agreements, healthcare professional agreements, vendor agreements, and statements of work), whether on BioCryst templates or third-party forms, using approved playbooks and negotiation guidance, under attorney supervision. · Manage communications with internal stakeholders and counterparties throughout the contracting process and identify and escalate non-standard or higher-risk terms to the appropriate attorney. · Serve as the primary Legal contact for contract administration requests, including retrieving agreements. · Prepare first drafts and revisions of amendments, termination notices, assignment documents, and other routine contract documents. · Maintain contract records in contract management systems and shared repositories, ensuring accuracy, completeness, and version control. · Prepare contract summaries for attorneys and internal stakeholders responsible for implementing material contractual requirements · Assist attorneys with legal research, document review, and preparation of supporting materials, as appropriate. · Maintain deadlines, generate status reports, and ensure timely completion of tasks. Project Management & Operational Support · Manage and track legal and compliance-related projects, including timelines, deliverables, dependencies, and status reporting. · Coordinate cross-functional stakeholders to ensure projects move forward efficiently and deadlines are met. · Develop and maintain project plans, trackers, dashboards, and meeting materials. · Support process improvement initiatives related to contracting, legal operations, and compliance workflows. · Assist with implementation and ongoing use of legal systems and tools (e.g., contract lifecycle management platforms, intake tools). · Assist with the creation of Purchase Orders and spend tracking for Legal vendors. Compliance & Administrative Support · Assist with calendars, meeting agendas, and planning for the Legal leadership team, including logistics such as meeting room booking and working with internal and external parties for availability and scheduling. · Schedule and plan travel for senior leaders in Legal. · Support compliance and governance activities by maintaining documentation, logs, and audit-ready records. · Assist with tracking training, certifications, disclosures, and other compliance-related requirements, as directed. · Prepare reports, summaries, and presentations for Legal and Compliance leadership. · Handle confidential and sensitive information with discretion and professionalism. · Other duties as assigned. EXPERIENCE & QUALIFICATIONS: Required: · Bachelor’s degree or paralegal certificate from an accredited program. · 5+ years of experience in a paralegal, contracts, or related role. · Experience managing multiple projects simultaneously. · Strong organizational, project management, and prioritization skills. · Excellent written and verbal communication skills. · High level of attention to detail and accuracy. · Proficiency with Microsoft 365 (Word, Excel, PowerPoint, Outlook, Teams, SharePoint). · Able to thrive in a fast-paced, dynamic environment with a high degree of professionalism and confidentiality. Preferred: · Experience in the pharmaceutical, biotechnology, healthcare, or other regulated industry. · Familiarity with employment-related agreements and human resource matters. · Familiarity with contract lifecycle management tools and legal intake workflows. · Exposure to compliance, governance, or audit support activities. The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time. BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. Passionate. Smart. Motivated. We’re all these qualities—but most importantly, we’re committed to making a difference in the lives of those living with hereditary angioedema (HAE) and other rare diseases. If you’re someone who turns challenges into triumphs and aims to achieve beyond what you think is possible, we’re waiting for you. Culture is the fabric that binds us together and makes our company a special place to work. We are powered by our people, and every employee can provide valuable input on how we can achieve our goals through a culture of accountability. Our bold thinking comes from our “people-first” perspective, where we are united across fronts to do the right thing for patients, without fear of failure—but with embracing the learnings gleaned from setbacks that fuel our self-awareness. We value ownership, integrity, and the ability to laugh and learn from our mistakes. We are proud of our ability to reward innovative thinking and grow from personal and professional discovery.

Sr. Paralegal - Generalist.

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