Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Resnek Family Center for Primary Sclerosing Cholangitis Research The Chief Scientific Officer, Research Strategy and Operations serves as the senior scientific and operational leader for the Resnek Family Center for Primary Sclerosing Cholangitis Research. Working in close partnership with the Principal Investigator, this role provides high-level leadership across research strategy, program operations, personnel management, regulatory oversight, and institutional collaboration in support of a complex and growing research enterprise. This individual will play a pivotal role in shaping and executing the Center’s scientific and operational vision across basic, translational, and clinical research initiatives. The Executive Lab Director will align people, processes, and resources to advance scientific priorities, strengthen organizational infrastructure, and position the lab for sustained impact, growth, and cross-disciplinary collaboration. The ideal candidate is an accomplished research leader with a strong scientific foundation, exceptional operational judgment, and the ability to lead through influence in a highly collaborative academic medical environment. Qualifications Responsibilities Strategic Scientific and Program Leadership Serve as a senior partner to the Principal Investigator in defining and advancing the scientific and operational vision of the Resnek Family Center. Provide leadership across a diverse research portfolio spanning basic, translational, and clinical investigation. Guide the planning, prioritization, and execution of research initiatives to ensure alignment with programmatic goals and institutional standards. Contribute to scientific analysis, interpretation, and the development of presentations, reports, publications, and other scholarly outputs. Anticipate scientific and operational barriers and drive solutions that support research progress and program growth. Research Operations and Infrastructure Lead all aspects of laboratory operations, ensuring a high-performing, well-organized, and scalable research environment. Oversee laboratory infrastructure, workflows, scheduling, space allocation, equipment, vendor relationships, and inventory systems. Design and implement operational systems that enhance efficiency, resource stewardship, and execution across the research enterprise. Establish best practices and operating procedures that support consistency, quality, and long-term sustainability. Leadership, Talent, and Culture Provide leadership, supervision, and mentorship to research staff, trainees, and laboratory personnel. Build an engaged, inclusive, and accountable team culture grounded in collaboration, professionalism, and scientific excellence. Oversee talent-related processes including onboarding, training compliance, role clarity, and day-to-day staff support. Help develop internal capacity by coaching team members and strengthening operational and research capabilities across the lab. Regulatory, Compliance, and Risk Oversight Provide senior oversight for research compliance, laboratory safety, biosafety practices, and regulatory readiness. Direct the preparation, maintenance, and monitoring of relevant research and animal protocols. Serve as the primary liaison to institutional compliance offices, animal care programs, and administrative partners on regulatory and operational matters. Ensure systems are in place to support audit readiness, protocol renewals, and compliance continuity. Financial and Resource Stewardship Lead budget planning, expenditure oversight, and financial forecasting for the laboratory and related research activities. Partner with finance, grants, and administrative teams to support sound post-award management and operational decision-making. Monitor resource utilization and identify opportunities for cost containment, vendor optimization, and long-term sustainability. Provide the Principal Investigator with strategic insight into spending trends, operational needs, and resource planning. Institutional and External Partnership Development Represent the lab in interactions with institutional leaders, researchers, clinicians, and external collaborators. Strengthen coordination across multidisciplinary teams and support the development of collaborative initiatives and shared resources. Serve as a trusted connector across scientific, operational, and administrative stakeholders to enable effective execution and partnership. Qualifications Bachelor’s degree in a biological, chemical, biomedical, or related scientific field required. Significant experience in research leadership, laboratory operations, or research administration in an academic medical center, hospital, or biomedical research environment required. Preferred Qualifications Advanced degree preferred; Master’s degree or PhD strongly favored. Demonstrated success overseeing complex research programs, teams, compliance processes, and budgets strongly preferred. Experience working across institutional systems and with multidisciplinary collaborators preferred. Leadership Profile Executive-level judgment and strategic thinking. Strong people leadership and team development capabilities. Operational sophistication and the ability to build high-functioning systems. Excellent communication and relationship management skills. Collaborative leadership style with the ability to influence across functions and levels. Commitment to scientific rigor, operational excellence, and mission-driven research. Working Environment This position is based at the Resnek Family Center for Primary Sclerosing Cholangitis Research and supports a high-impact research program dedicated to advancing understanding and treatment of primary sclerosing cholangitis through integrated basic, translational, and clinical Additional Job Details (if applicable) Remote Type Hybrid Work Location 20 Shattuck Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Are you ready? Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.

Senior Research Scientist.

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