About the Team: Enterprise Systems is the backbone of GSK’s internal operations in Digital & Tech, enabling GSK Global Functions teams such as Finance, Procurement, HR, Legal, Compliance, (Workplace & Real Estate Facilities) WREF, (Communications & Government Affairs) CGA and Corporate Secretariat to run seamlessly. This team designs and delivers cutting-edge digital platforms that power critical processes, ensuring efficiency, compliance, and scalability across the enterprise. Enterprise Systems Management & Business Operations delivers digital solutions that support Enterprise Systems running as a high-performing organisation. This team drives financial discipline, operational rigour and strategic alignment across the (Enterprise Systems) ES portfolio that safeguard GSK’s integrity and reputation globally. By joining this team, you’ll help shape systems that support thousands of employees worldwide, driving innovation and reliability in the tools that keep GSK moving forward. Job Purpose: The Principal Developer Siemens OpCenter designs, develops, tests, and supports (Manufacturing Execution System) MES solutions using Siemens OpCenter Execution Pharma. The role translates business and manufacturing requirements into reliable, secure, and compliant system solutions, including configurations, databases, integrations, and custom applications. The role supports troubleshooting of complex technical issues, uses approved AI-assisted development tools to improve efficiency, and ensures all solutions meet quality, security, data integrity, and (Good Practice) GxP requirements. The Principal Developer- Siemens OpCenter also promotes standardization, reusable solutions, and best practices across MES platforms and teams. Key Responsibilities: Design, configure, develop, and implement MES solutions using Siemens OpCenter Execution Pharma. Translate business and manufacturing requirements into technical solutions by developing and maintaining system integrations, database objects, and custom applications that support operational and business needs. Perform testing, deployment, and validation activities to ensure system reliability and compliance. Troubleshoot and resolve MES application issues and provide production support. Collaborate with business users, project teams, and vendors to deliver MES projects while leveraging approved development and AI-assisted tools to enhance productivity, solution quality, and project outcomes. Create and maintain technical documentation, design specifications, and support materials. Contribute to standardization, best practices, and continuous improvement initiatives. Ensure compliance with GxP, data integrity, cybersecurity, and company standards while providing technical guidance, expertise, and knowledge sharing to support team capability and consistent system practices. Participate in system upgrades, enhancements, and lifecycle management activities Develop expertise across MES platforms, software technologies, and AI tools to effectively support and deliver solutions across multiple MES systems. Use AI-assisted development as the default way of coding, testing, reviewing and documenting, and validate all AI-generated output for quality, security, data integrity and GxP before release. Implement version control and automated build, test, and deployment practices where supported, achieving improved release quality and deployment efficiency. Monitor production performance, proactively identify and eliminate root causes of issues, reducing recurring incidents and improving system reliability and availability. Basic Qualifications: Bachelor’s or master’s degree in engineering, Computer Science, Information Technology, Automation, Data, Life Sciences or a relevant technical discipline, or equivalent practical experience. Relevant technical, AI, cloud, integration, automation, data, validation, cyber security or engineering certifications. Minimum 5+ years of hands-on technical engineering experience in complex enterprise or operational technology environments. Experience in leading MES solution delivery across products, platforms and sites. Experience in software development, database technologies, system integrations and industrial connectivity solutions within MES or manufacturing environments. Experience in technical review, troubleshooting and root-cause analysis. Experience in coordinating teams and vendors to deliver compliant and reliable solutions. Experience in managing technical risk, ensuring data integrity and compliance, and supporting audits and inspections. Experience in working with AI-assisted development tools and applying validation, security, compliance and quality controls for software delivery. Experience in mentoring engineers and supporting best practices and standardisation. Preferred Qualifications: Experience in problem-solving, technical leadership and communication. Experience in developing solution designs, managing technical documentation and supporting compliant system delivery. Experience in integrations, data management, security, quality and change control processes. Experience in collaborating across teams, mentoring engineers and supporting standardisation, automation and continuous improvement. #AGTech #GSK-LI Skills Agile Methodology, API Management, CI/CD, Cloud Based Services, Computer Programming, Configuration Management (CM), Containerization, Database Management, High Availability (Inactive), Infrastructure As Code (IaC), Microservices Architecture, Network Security, Operating Systems (OS), System Monitors, Version Control System Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Inclusion at GSK: As an employer committed to Inclusion, we encourage you to reach out if you need any adjustments during the recruitment process. Please contact our Recruitment Team at [email protected] to discuss your needs. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. It has come to our attention that the names of GlaxoSmithKline or GSK or our group companies are being used in connection with bogus job advertisements or through unsolicited emails asking candidates to make some payments for recruitment opportunities and interview. Please be advised that such advertisements and emails are not connected with the GlaxoSmithKline group in any way. GlaxoSmithKline does not charge any fee whatsoever for recruitment process. Please do not make payments to any individuals / entities in connection with recruitment with any GlaxoSmithKline (or GSK) group company at any worldwide location. Even if they claim that the money is refundable. If you come across unsolicited email from email addresses not ending in gsk.com or job advertisements which state that you should contact an email address that does not end in “gsk.com”, you should disregard the same and inform us by emailing [email protected], so that we can confirm to you if the job is genuine. We are a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site.

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