Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary The Koo Laboratory in the Division of Infectious Diseases at Brigham and Women’s Hospital, Harvard Medical School, is seeking highly motivated post-doctoral Research Fellow candidates. In the Koo laboratory, we are dedicated to the development and application of novel diagnostic approaches for infections in immunocompromised hosts and the delineation of the epidemiology and pathophysiology of opportunistic pathogens, especially fungi, in these patient populations. The candidate will be expected to have experience, or a high capacity to learn, murine pneumonia models, and molecular genetic techniques including spatial transcriptomic studies, and microbiologic/mycologic laboratory techniques. The team will include the Principal Investigator and other collaborating faculty, research scientists, postdoctoral fellows, and research assistants. We are seeking a Research Fellow with the enthusiasm to develop projects that will contribute to diverse and highly collaborative research programs. The new hire will be appointed as a Research Fellow at the Massachusetts General Brigham and at the Harvard Medical School. Qualifications IMPORTANT – APPLICATION INSTRUCTIONS This is a courtesy posting. Please do not submit your application through the Workday "Apply" button. To be considered for this position, email your CV and cover letter to Sophia Koo at [email protected] Applications submitted only through Workday will not be forwarded to the hiring manager and may not be reviewed. PRINCIPAL DUTIES AND RESPONSIBILITIES: • Design, execute, and interpret research experiments • Learn any number of molecular genomics techniques including single-cell RNAseq (scRNAseq), spatial transcriptomics, and other methods • Maintain murine models and process murine tissues for more detailed evaluation • Use advanced analytical chemistry techniques to define the breath volatile metabolite profile of patients with various bacterial, viral, and fungal pneumonias. • Analyze mass spectroscopic and differential mobility spectroscopic data from laboratory experiments. • Maintain a detailed record of experiments in a laboratory notebook • Independently follow detailed protocols while working closely with a wide range of lab members (i.e., graduate students, postdocs, research assistants, staff scientists) • Assist in training new Research assistants and Postdoctoral Fellows • Responsible for troubleshooting problems and instructing others in highly specialized techniques. • Investigate, create, and develop new methods and technologies for research advancements. • Preparation of written data reports, including methodology, figure preparations, written description of the study in the form of manuscripts and/or progress reports. • Contribute to research presentations at local, national, and international meetings. • Oversight of laboratory research assistants and students participating on the projects, including training them, and assisting them with experimental design and implementation. • Organize and/or draft material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation. The Research Fellow will be situated at Brigham and Women’s Hospital under the guidance and mentorship of Dr. Sophia Koo. Qualifications The ideal candidate should have received (or expect to receive soon) a MD or a PhD in a relevant biological field. Excellent English verbal and written communication skills Able to work both independently and in a team Interest in learning and troubleshooting new molecular biology techniques Familiarity with animal modeling of disease Excellent organizational and communication skills Excellent interpersonal skills and the ability to supervise and train staff effectively. Ability to prioritize tasks, set deadlines, and adapt to shifting priorities in response to changing deadlines and needs of the lab. EDUCATION: Minimum Required: Doctoral Degree Preferred: Doctoral Degree EXPERIENCE: Required: Recent MD or PhD graduate, 1+ years of experience in a research-related field required SUPERVISORY RESPONSIBILITY: May oversee research assistants, Technicians, Technologists, and Students. No authority to hire/promote/terminate WORKING CONDITIONS: Work will be performed in the Thorn Research Building on the Brigham and Women's Hospital main campus, in Boston, MA. Additional Job Details (if applicable) The compensation range for this role is between $71,750 - $81,179. Candidate experience is thoughtfully considered throughout the recruitment process, and those with significant experience may be considered for compensation above the starting range listed, as consistent with organizational guidelines and internal equity Years of experience 0 $71,750 - $73,544 1 $73,544 - $75,382 2 $75,382 - $77,267 3 $77,267 - $79,199 4+ $79,199 - $81,179 Remote Type Onsite Work Location 20 Shattuck Street EEO Statement: 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Are you ready? Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.

Research Fellow.

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