This is what you will do: The Medical Science Liaison (MSL) is a field-based scientific expert that strategically supports the medical and scientific objectives of Alexion, AstraZeneca Rare Disease’s product/s across the product/s life cycle. The individual is a peer scientific expert who communicates accurate and applicable science to Healthcare Practitioners (HCPs) within a geographic area. The individual manages and maintains collegial and professional relationships with HCPs and Key Opinion Leaders (KOLs) and identifies and facilitates collaboration opportunities with Alexion, AstraZeneca Rare Disease. The MSL combines strong business acumen and clinical expertise and serves as a peer-to-peer liaison internally to Medical Directors, USMA Leadership Team, cross-functional partners and externally (HCPs & KOLs). The MSL should be able to identify problems early on, seek appropriate help and counsel to work past any barriers, and innovate in order to achieve medical goals and objectives. You will be responsible for: HCP relationship management Evaluates their territory to profile and identify the HCPs to engage and build relationships with, as well as identify, important centers of excellence Develops clear, succinct, impactful HCP engagement plans, aligned with medical strategic goals and objectives. Evaluates and refines plans as needed per the progress against the quarterly focus priorities Gains HCPs’ trust and respect by effectively providing and communicating relevant scientific/medical information on the company’s products and disease states Gathers and disseminates HCP insights as appropriate internally to help inform medical strategy Develops strong working relationships in different external business settings Scientific knowledge and training Keeps current with scientific knowledge within assigned products and therapeutic area Supports scientific exchange of product/disease state with external stakeholders (HCPs) as needed Provides relevant scientific information to other internal teams and functions as appropriate Demonstrates a functional understanding of real-world evidence and HEOR Research & Development Demonstrates a strong understanding of clinical study design and protocols Ensures HCPs and stakeholders receive focused and balanced clinical and scientific information Develops expertise in applicable research outcomes to credibly conduct effective discussion with HCPs Supports applicable externally sponsored research and clinical trials, as appropriate US Healthcare system knowledge Acquires knowledge of the current US healthcare system environment and its impact on the rare disease ecosystem Builds a basic understanding of the foundations of managed markets Acquires a basic understanding of the flow of information in managed care and government organizations You will need to have: Minimum Education MD, PharmD, or PhD in biological sciences strongly preferred Clinical experience in a relevant therapeutic area OR track record of success as an MSL Minimum Experience 0+ years of Industry experience is preferred but not mandatory; if no industry experience, therapeutic area experience (Hematology/Nephrology/Transplant) is preferred Specific Knowledge, Skills, and Abilities Has excellent communication skills (oral and written) Energetically embraces responsibilities and demonstrates the ability to achieve goals Has a strong personal initiative Functions well as part of a cross-functional team Exhibits excellent time management Able to work independently Demonstrates leadership skills and high-level job competencies Additional Role Requirements Office is home based. Travel within region 3-4 days per week with 1-2 office days per week Person should be able to travel minimum ~70% time Required travel to medical meetings, team meetings and other group meetings (including possible weekends, as dictated by conference schedule) Candidate is required to live within the territory The duties of this role are generally conducted in a field environment. As is typical of a field-based role, employees must be able, with or without an accommodation, to travel by public transportation, automobile, train, or plane; work comfortably in a clinical setting; use a computer; engage in communications via phone, video, and electronic messaging; problem solve; engage in complex and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours At AstraZeneca, we are taking bold action on climate because we recognize the connection between healthy people and a healthy planet. As part of our flagship Ambition Zero Carbon program, we have committed to a fully electric vehicle (EV) fleet by the end of 2025, which means that all of our drivers will be assigned an EV. Ability to travel within territory on a regular basis which will include frequent overnight and weekend travel. Valid driver’s license and clean driving record required). All activities should be conducted per Alexion, AstraZeneca Rare Disease policies. Date Posted 23-Oct-2026 Closing Date 05-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. For over three decades, patients and their caregivers have been at the center of everything we do. Every day, we are inspired to follow the science and think differently to create better outcomes for them and their families. Our mission is driven by understanding who they are as unique individuals, not solely defined by their diseases. We’re a leading rare disease company with a diversified projects. Our pioneering legacy in rare diseases is rooted in being the first to translate the complex biology of the complement system into transformative medicines over the past three decades. Today, we continue to push the boundaries of science and deepen our understanding of rare diseases with patient-centricity at the core. This knowledge allows us to innovate and evolve into new areas where needs are unmet and provide an opportunity to help people fully live their best lives.

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