Job Title: Associate Director, Supply Chain Planning Location: Hamilton, Ontario Onsite 5 days/week Description: Fusion Pharmaceuticals, part of the AstraZeneca Group, is redefining precision oncology with next‑generation radioconjugates that deliver powerful alpha‑emitting payloads directly to tumors. Our pipeline spans multiple first‑in‑class programs—backed by a GMP‑compliant, brand new radiopharmaceutical facility in Hamilton, we’re turning groundbreaking science into real‑world impact for patients. Join us at the forefront of radiopharma innovation and be part of turning breakthrough science into meaningful outcomes for patients—come build what’s next with us! The Role: We are seeking a strategic and analytical Associate Director of Supply Chain Planning to lead clinical supply forecast planning and drive cross-functional alignment. In this vital leadership role, you will be the linchpin for global clinical supply visibility, translating complex clinical trial protocols and enrollment forecasts into executable supply plans. You will direct the Sales and Operations Planning (S&OP) processes. You will focus on identifying risks early and serve as the main contact for supply chain health with collaborators inside and outside the company. Responsibilities: Host recurring Sales and Operations Planning (S&OP) meetings to align cross-functional partners. Lead the systematic collection and consolidation of clinical trial drug demand from multiple studies, translating Phase 1–3 clinical trial protocols and enrollment forecasts into executable supply plans. Develop and deliver high-level Demand and Supply reports, collaborate cross-functionally to define and implement long-range and short-range supply strategies. Proactively identify and communicate supply chain risks, establishing early-warning indicators for potential bottlenecks, shortages, or timeline shifts, and driving risk mitigation strategies. Ensure internal and external manufacturing alignment with evolving S&OP demand forecasts and scheduling requirements. Support annual budgeting process and monitor financial forecasts. Develop and maintain Standard Operating Procedures (SOPs) and Work Instructions for core departmental processes and supply activities to ensure GxP compliance and consistency. Plan and oversee patient doses and overall manufacturing operations. Participate in ongoing optimization of planning workflows, system enhancements, and change control assessments. Perform other related operational duties as required by the business. Qualifications: Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or Finance. A Master’s degree or MBA is highly preferred. 8+ years of experience in production planning, scheduling, or supply chain experience, preferably within the pharmaceutical, biotech, or clinical research sectors. Expert-level capability in analyzing complex datasets, modeling supply scenarios, and presenting risk/demand forecasts to executive partners. Strong command of ERP/MRP systems(e.g. SAP or specialized clinical supply management systems like Perceptive RTSM) and advanced data management tools (e.g. Microsoft Excel, SharePoint, and workflow automation tools). Familiarity with GMP (Good Manufacturing Practices) and Standard Operating Procedures within a regulated manufacturing environment. Outstanding ability to synthesize complex clinical data into clear, proactive risk communications for both technical and non-technical partners. Able to work flexible hours to accommodate global time zones as needed. Desirable: Familiarity with clinical trial phases (Phase I–III), blinding/randomization concepts, and the strict timelines required for patient-specific dosing. Proven experience in cell therapy or radiopharmaceutical supply chain operations is a plus. Familiarity with Global clinical distribution networks, import/export regulations, and short shelf-life material logistics. Experience leading change control assessments, deviation investigations, or CAPA (Corrective and Preventive Actions) workflows within a GxP environment. Great People want to Work with us! Find out why: GTAA Top Employer Award for 11 years Top 100 Employers Award Canada’s Most Admired Corporate Culture Learn more about working with us in Canada View our YouTube channel Are you interested in working at AZ, apply today! AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing [email protected] ⠀ Annual base salary for this position ranges from 123,997.60 to 162,746.85. AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances. In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program. We are using AI as part of the recruitment process. This advertisement relates to a current vacancy. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

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