ROLE SUMMARY The Director, QSEO Digital Strategy & Operations Lead is responsible for developing and driving the Quality, Safety, Environment & Operations (QSEO) Digital strategy and translating QSEO business priorities into an integrated portfolio of Digital investments, capabilities and transformation initiatives. The role provides the strategic connection between QSEO business priorities and Digital execution, ensuring investments are appropriately prioritized, governed and integrated to advance business objectives and deliver measurable value across QSEO and Pfizer Global Supply (PGS). The Director provides strategic and subject-matter leadership across Digital strategy, portfolio management, governance, investment planning, operating-model effectiveness, adoption and value realization. The role establishes the mechanisms needed to create transparency across the Digital portfolio, evaluate competing priorities and dependencies, monitor progress and value, and enable informed decision-making regarding resources, investments and delivery. Working across QSEO pillars, PGS functions and Digital partners, the Director leads complex, cross-functional teams to support initiatives and stakeholders with diverse priorities and accountabilities. The role applies deep functional expertise, business acumen and independent judgment to anticipate risks, identify opportunities, develop recommendations and resolve complex issues that may affect portfolio delivery or QSEO objectives. ROLE RESPONSIBILITIES Develop and drive the QSEO Digital strategy, translating business priorities into an integrated portfolio, roadmap and mid-term implementation plans. Lead Digital portfolio planning, prioritization and budget management, evaluating investments, resource requirements, dependencies, risks and anticipated business value. Provide strategic recommendations to senior leaders and governance forums regarding portfolio priorities, investment trade-offs and delivery risks. Lead QSEO Digital Governance and the VISTA forum, enabling informed decision-making, alignment and accountability across QSEO pillar priorities. Establish and continuously improve the QSEO Digital operating model, value-delivery RACI, decision rights and stakeholder engagement approach. Provide strategic oversight of system deployment timelines, plans of record, financial commitments and critical program milestones, driving resolution or escalation of material issues. Lead complex strategic initiatives by partnering Business System Owners, Global Process Owners, Artificial Intelligence teams, Core Solutions for Quality, Digital, PGS Data, Analytics & AI and other key stakeholders. Establish consistent approaches for measuring Digital adoption, portfolio performance, business outcomes and realized value. Guide Digital support for priority QSEO programs, including the digitization and enhancement of Quality Management System and Environment, Health & Safety processes. Lead QSEO IMEx governance, including performance reporting, resource visibility, risk assessment and escalation. Identify and advance opportunities to simplify processes and responsibly apply Digital, analytics, automation and artificial intelligence capabilities to improve productivity, compliance and decision-making. Serve as a trusted advisor and recognized subject-matter expert in Digital strategy, portfolio governance and transformation. BASIC QUALIFICATIONS Bachelor’s degree in a scientific, engineering, technology, data, business or related discipline with at least eight years of relevant experience; or a master’s degree with at least seven years of relevant experience; or a doctoral degree with at least five years of relevant experience. Significant experience in Digital strategy, Digital transformation, portfolio management, program leadership or business operations. Demonstrated expertise in translating business strategy into Digital priorities, portfolio plans and measurable outcomes. Proven experience leading complex, cross-functional initiatives within a global, highly matrixed organization. Experience managing portfolio priorities, budgets, resource requirements, interdependencies, risks and value realization. Demonstrated ability to exercise independent judgment and develop recommendations for highly complex and ambiguous business challenges. Proven ability to influence senior leaders, mobilize cross-functional stakeholders and drive outcomes without direct authority. Strong business acumen and the ability to connect Digital investments with business, operational and compliance outcomes. Excellent written and verbal communication skills, including the ability to synthesize complex information and present clear recommendations to senior leadership. Demonstrated Digital and AI fluency, including the ability to evaluate and apply emerging capabilities to improve productivity, processes and decision-making. PREFERRED QUALIFICATIONS Advanced degree in a relevant discipline. Experience in pharmaceutical manufacturing, quality, safety, environmental operations or another highly regulated environment. Experience leading enterprise or business-unit Digital portfolio governance, roadmap development, investment planning and value realization. Experience advancing the digitization of Quality Management System or Environment, Health & Safety processes. Demonstrated expertise working across business, process-owner and Digital or technology organizations. Experience leading organizational change, Digital adoption or transformation communications. Project, program or portfolio management certification. Experience applying analytics, automation or artificial intelligence capabilities to complex business and operational challenges. PHYSICAL/MENTAL REQUIREMENTS Ability to evaluate multiple complex and concurrent inputs, exercise sound judgment and develop clear, actionable recommendations. Ability to manage competing priorities and operate effectively in a complex, matrixed and globally distributed environment. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Periodic participation in meetings outside standard working hours may be required to support global stakeholders. Occasional business travel may be required based on portfolio and program needs. Work Location Assignment: Hybrid Relocation Support: NO Last date to apply: 11/4/2026 The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers. Information & Business Tech A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

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