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Job Title: Senior MSAT Specialist, Materials Career Level: D About Singapo0re ADC Site: Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore — a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence. This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus: Small molecule- chemical API production Large molecule- monoclonal antibody manufacturing Conjugation Fill-and-finish operations, including sterile filling and lyophilization Final secondary packaging The campus will be equipped with innovative digital and automation infrastructure, enabling autonomous manufacturing powered by artificial intelligence. In addition, it will be designed for carbon neutrality, embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologic's manufacturing. In Manufacturing Science and Technology Team, we are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a “make-it-happen” attitude. Joining us means contributing to a project that will not only transform AstraZeneca’s global supply chain but also advance life-changing medicines for patients everywhere. If you’re ready to shape the future of biologics and be part of a once-in-a-generation project, we want you on our team. Introduction to the Role: Are you ready to define the standards for manufacturing materials and single-use systems that safeguard patient safety and product quality? In this senior role, you will be the go-to expert for materials and product-contact components across biologics, API, and fill-finish operations, shaping how we qualify, manage, and continuously improve the materials that touch every medicine we make. You will lead risk-based qualification and lifecycle strategies that directly influence manufacturing robustness, regulatory compliance, and speed to patients. Partnering closely with the Director of Product Technical Transfer and cross-functional teams, you will translate science into reliable, scalable solutions that keep our operations resilient and our pipeline moving. Accountabilities: Material Qualification Leadership: Strategize and continuously improve material qualification, lifecycle management, and supplier assessment programs to ensure compliance, product quality, and manufacturing robustness. Risk-Based Assessment and Qualification: Lead risk assessments, technical evaluations, and qualification activities for manufacturing materials, product-contact components, and single-use systems, ensuring fit-for-use and audit-ready documentation. E&L Strategy and Patient Safety: Drive extractables and leachables strategies, material compatibility assessments, and scientific justifications that uphold regulatory compliance and protect patients. Technology and Supplier Innovation: Evaluate and implement new materials, technologies, and supplier solutions to improve reliability, scalability, and operational performance across biologics and sterile manufacturing. Technical Escalation and Problem Solving: Serve as the primary point of technical escalation, resolving complex challenges or coordinating cross-functional solutions; apply advanced knowledge of manufacturing systems, equipment, and regulatory guidelines to drive effective investigations and process improvements. Process Excellence and Change Implementation: Support the implementation of changes, mitigate risks, and integrate innovative technologies or methodologies; align technical goals with operational and quality objectives while meeting business priorities and customer expectations. Capability Building and Standards: Mentor MSAT material specialists, establish technical standards and best practices, and enable capability development across teams; advise and coach colleagues to strengthen expertise and promote consistent ways of working. Cross-Functional Collaboration and External Engagement: Collaborate with internal regulatory groups, Quality, Operations, Supply Chain, planning and purchasing, central project teams, and other sites; engage external suppliers and agencies to overcome obstacles and identify opportunities for enhancement. Communication and Leadership Visibility: Communicate technical insights, recommendations, and potential innovations effectively to technical and non-technical stake-holders, including senior leadership; foster adoption of digital solutions and track effectiveness. Continuous Improvement and Industry Awareness: Stay informed on industry trends and organizational developments to continuously improve technical practices and keep expertise current; engage teams to adopt digital tools and data-driven decision making. Essential Skills/Experience: Degree in technical or scientific field OR Technical/Associate/Vocational diploma with equivalent experience Extensive experience in regulated manufacturing environments Deep expertise in manufacturing or packaging operations Proven ability to resolve complex technical issues Strong knowledge of GMP, SHE, SOPs, compliance frameworks Experience in applying project management principles Understanding of manufacturing and engineering landscapes Ability to explain technical decisions to diverse stake-holders Desirable Skills/Experience: Hold or pursue recognised professional certification Broad understanding of product supply chain Knowledge of interdependence between machinery / equipment, components/ materials, and process performance Ability to connect supply chain operations with process optimization When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Here, your technical leadership will shape how molecules become medicines through disciplined execution and bold problem solving. You will work with modern digital tools, advanced single-use technologies, and lean practices alongside colleagues who combine curiosity with kindness, ambition with humility. We bring diverse expertise together to tackle complex manufacturing challenges, accelerate delivery, and reduce environmental impact, so that every improvement you make resonates from the factory floor to patients and their families. Call to Action: Ready to set the benchmark for materials technical excellence and see your decisions translate into reliable, life-changing medicines - what will you build with us next? Date Posted 14-Oct-2026 Closing Date 31-Oct-2026 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca. Details Details Details 
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Astrazeneca
Singapore, Singapore
Senior MSAT Specialist, Materials.
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