Job Description The IT Senior Program Manager is responsible for guiding the success and delivery of strategic technology programs, from conception to operation. The role creates a compelling program vision and drives business value. This position bridges technology, business, and user experience, blending a program-focused approach with agile methods to consistently deliver value and ensure that technology strategies match business objectives. This role oversees program vision and execution, while promoting collaboration, innovation, and ongoing improvement across cross-functional delivery teams. Typical Accountabilities Owner and driver of the IT Program Plan: Work closely with stakeholders to develop, articulate, and share the plan, dependencies, Risks and Issues, making sure all teams including engineering, design, and business - are aligned. Serves as the primary program orchestrator and is responsible for driving program and ensuring “value” delivery. Develops program-focused delivery teams and adopts agile methodologies to continually enhance the program through iterative improvements. Manage the program backlog, translate business needs into detailed requirements, and prioritize features based on business value, user feedback, and technical feasibility. Financial Accountability: Be accountable for Program finance, including forecasting, budget management, and timely accruals. Define and track Key Performance Indicators (KPIs) including measuring both value and outcomes (as desired with investment case). Act as the primary point of contact between IT leaders and engineering/technical teams. Lead vendor management, including negotiation of deliverables, acceptance criteria, and costs. Risk & Compliance Management: Proactively identify, assess, and mitigate risks (technical, market, project) and ensure compliance with internal and external regulations (e.g., GxP, if applicable). Education, Qualifications, Skills and Experience Essential Ability to manage senior stakeholders and build IT Program vision and roadmaps. Extensive experience delivering medium to large-scale IT Programs and programs (USD 5M+ or multi-disciplinary delivery teams >15). Proven accountability for IT Program finance, including forecasting and timely accruals. Hands-on, practical experience delivering programs and utilizing modern tools and methodologies such as Agile. Strong program-centric mindset with experience managing the program lifecycle (e.g., Concept to DevOps, backlog prioritization, KPI analysis). Background in manufacturing, supply chain, and/or quality domains (GxP, MES, etc.). Excellent communication, negotiation, and conflict resolution skills, with experience engaging C-level executives. Strong vendor management capabilities. Strategic & Analytical Thinking: Ability to use data and user feedback to make decisions. User Empathy: A customer-centric mindset. Desirable Experience working in the pharmaceutical industry. Familiarity with GXP, GCP practices. Date Posted 21-10月-2026 Closing Date 30-10月-2026 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

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