Company Overview:
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Director, Government Pricing & Contract Operations is a key leader within U.S. Pricing & Contracting responsible for ensuring the compliant execution, oversight, and continuous improvement of government pricing and contract administration processes. This role serves as the internal subject matter expert for government pricing regulations, methodologies, and reporting requirements while overseeing external vendors responsible for calculation, validation, submission, and operational support activities.
The Director will partner closely with Market Access, Finance, Legal, Compliance, Trade, and Commercial Operations to evaluate the impact of pricing and contracting strategies on government price reporting and contractual obligations. This position is accountable for maintaining a robust compliance framework, ensuring operational excellence, and driving effective vendor governance across all government pricing and contract administration activities.
This role is based in Waltham, MA without the possibility of being fully remote.
Primary Responsibilities Include:
Government Pricing & Reporting
- Serve as the internal expert on U.S. Government Pricing programs, including AMP, Best Price, ASP, Medicaid Drug Rebate Program, 340B, Non-FAMP, FCP, and Federal Supply Schedule pricing.
- Oversee third-party vendors responsible for government pricing calculations, validations, submissions, and reporting.
- Review and approve pricing methodologies, assumptions, and reporting outputs to ensure compliance and accuracy.
- Assess the impact of pricing, contracting, distribution, and market access strategies on government price reporting.
- Monitor and implement regulatory and policy changes, including CMS, OIG, and Inflation Reduction Act (IRA) requirements.
- Maintain government pricing policies, SOPs, controls, and documentation to support compliance and audit readiness.
- Lead responses to audits, compliance reviews, and governmental inquiries.
- Partner with Finance to support rebate accruals, forecasting, and financial reporting requirements.
- Drive process improvements, automation, and data quality initiatives to enhance operational efficiency and compliance.
Contract Operations & Administration
- Provide leadership and oversight for contract operational processes, ensuring accurate implementation and administration of approved contract terms.
- Ensure accurate maintenance of contract records, documentation, eligibility files, and contract management systems.
- Oversee rebate administration processes, including validation, adjudication, dispute resolution, and payment activities managed through external vendors.
- Partner with Legal, Market Access, and Compliance to evaluate contract structures, operational feasibility, and government pricing implications.
- Drive continuous improvement initiatives to enhance operational efficiency, reporting and analytics capabilities, and performance measurement to support informed business decision-making and contracting strategies.
- Maintain contract documentation, controls, and procedures to support audit readiness and continuous improvement.
Leadership & Cross-Functional Collaboration
- Build strong partnerships across Market Access, Finance, Legal, Compliance, Trade, Commercial Operations, and external vendors.
- Lead cross-functional initiatives related to government pricing compliance, contract operations, and process improvements.
- Communicate complex pricing and contracting concepts to senior leadership and business stakeholders.
- Foster a culture of compliance, accountability, collaboration, and operational excellence.
Education and Skills Requirements:
- Bachelor's degree in Finance, Accounting, Economics, Business Administration, Healthcare Administration, or a related field.
- 10+ years of experience within the pharmaceutical or biotechnology industry, including significant experience in Government Pricing and/or Contract Operations.
- Deep knowledge of U.S. Government Pricing regulations and reporting requirements, including AMP, Best Price, ASP, Medicaid Rebates, 340B, Non-FAMP, FCP, and Federal Supply Schedule programs.
- Demonstrated experience managing external vendors supporting government pricing calculations, reporting, and contract administration activities.
- Experience overseeing rebates, chargebacks, contract administration, and market access operational processes.
- Strong understanding of pharmaceutical pricing, reimbursement, distribution, and contracting dynamics.
- Proven ability to interpret complex regulations and implement compliant business processes and controls.
- Strong leadership, analytical, project management, and communication skills with the ability to influence cross-functional stakeholders.
Preferred
- Advanced degree (MBA, MS, PharmD, JD, or equivalent).
- Experience in rare disease, specialty pharmaceutical, or biotechnology organizations.
- Experience supporting product launches and commercialization efforts.
- Experience with Government Pricing and Contract Management systems such as Model N, Revitas, SAP, or similar platforms.
- Knowledge of emerging government pricing regulations, including Inflation Reduction Act (IRA) requirements.
#LI-Onsite
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.